Tissue expression
Cell line expression
Protein structure
KCNA1
Potassium voltage-gated channel subfamily A member 1AEMK, HUK1, Kv1.1, MBK1, RBK1
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Boster Biological Technology | A01813-1 | Polyclonal |
WB
EL
ICC
IHC
FC
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Biorbyt | orb443192 | Polyclonal |
WB
EL
ICC
IHC
FC
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antibodies-online | ABIN2494831 | Polyclonal |
WB
EL
IHC
FC |
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GeneTex | GTX54834 | Polyclonal |
WB
ICC
IP
IHC |
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LSBio | LS-C405676 | Polyclonal |
WB
EL
IHC
|
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Supportive data in Antibodypedia
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Data in Antibodypedia (inconclusive)
Recommended by provider