Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L1501 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human NSUN2 monoclonal antibody, clone 4I35M22
- Antibody type
- Monoclonal
- Description
- NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4I35M22
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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