Tissue expression
Cell line expression
Protein structure
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductasecblE
This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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| Invitrogen Antibodies | Polyclonal |
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| Biorbyt | Polyclonal |
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| LSBio | Polyclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| Proteintech Group | 1 references | Polyclonal |
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