XPO7

The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors. [supplied by OMIM, Jul 2002]

Description

exportin 7

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

8:p21.3 (21919662 - 22006585)

Ensembl ID

ENSG00000130227  (ver. 99.38)

Orthologs

Mouse Xpo7: ENSMUSG00000022100

UniProt

Q9UIA9

neXtProt

NX_Q9UIA9

Human splice variants
Mouse splice variants