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- References [22]
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- Product number
- 16541-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16541-1-AP, RRID:AB_2062409
- Product name
- AXIN1 antibody
- Antibody type
- Polyclonal
- Description
- AXIN1 antibody (Cat. #16541-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references O-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma.
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway.
E3 ubiquitin ligase BTBD3 inhibits tumorigenesis of colorectal cancer by regulating the TYRO3/Wnt/β-catenin signaling axis.
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling.
Study of the mechanism by which Xiaoyan decoction combined with E7449 regulates tumorigenesis in lung adenocarcinoma.
Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells.
Effect of Jiedu Huayu decoction on oral mucosal Axin and β-catenin expression in oral submucosal fibrosis model rats.
XAV-939 inhibits epithelial-mesenchymal transformation in pulmonary fibrosis induced by crystalline silica via the Wnt signaling pathway.
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β.
SAC3D1 activates Wnt/β‑catenin signalling in hepatocellular carcinoma.
Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells.
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
YTHDF2 interference suppresses the EMT of cervical cancer cells and enhances cisplatin chemosensitivity by regulating AXIN1.
Targeting TRIM54/Axin1/β-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma.
AXIN2 Reduces the Survival of Porcine Induced Pluripotent Stem Cells (piPSCs).
Tankyrase-1-mediated degradation of Golgin45 regulates glycosyltransferase trafficking and protein glycosylation in Rab2-GTP-dependent manner.
A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway.
Exosomes derived from mineralizing osteoblasts promote ST2 cell osteogenic differentiation by alteration of microRNA expression.
HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.
Li J, Zhou W, Zhang J, Ma L, Lv Z, Geng Y, Chen X, Li J
Fundamental research 2025 Sep;5(5):2388-2396
Fundamental research 2025 Sep;5(5):2388-2396
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation.
Zhou C, Dong X, Li S, Xi Y, Liu Y, Qian X, Song Z, Zhou L, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Liu W, Xiong Y, Wang Z, Yan C, Zhang Z, Zhu H, Chen XZ, Song Z, Tang J
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
Signal transduction and targeted therapy 2025 Jun 30;10(1):205
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Zeng Y, Yang Y, Zeng F, Feng Q
mSystems 2025 Jul 22;10(7):e0169224
mSystems 2025 Jul 22;10(7):e0169224
Biodentine Counteracts the Aging Process of Human Dental Pulp Stem Cells Through Wnt/β-Catenin Pathway.
Zhang Q, Cao S, Zhang M, Wu D, Zhang C, Li J
International dental journal 2025 Aug;75(4):100819
International dental journal 2025 Aug;75(4):100819
E3 ubiquitin ligase BTBD3 inhibits tumorigenesis of colorectal cancer by regulating the TYRO3/Wnt/β-catenin signaling axis.
Ye K, Wang PC, Chen YX, Huang QZ, Chi P
Cancer cell international 2024 Sep 3;24(1):306
Cancer cell international 2024 Sep 3;24(1):306
COLEC10 inhibits the stemness of hepatocellular carcinoma by suppressing the activity of β-catenin signaling.
Cai MN, Chen DM, Chen XR, Gu YR, Liao CH, Xiao LX, Wang JL, Lin BL, Huang YH, Lian YF
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1897-1910
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1897-1910
Study of the mechanism by which Xiaoyan decoction combined with E7449 regulates tumorigenesis in lung adenocarcinoma.
Zheng X, Han Y, Gu L, Gao S, Lv Y, Li C
Journal of cellular and molecular medicine 2024 Jun;28(12):e18467
Journal of cellular and molecular medicine 2024 Jun;28(12):e18467
Wnt signaling blockade is essential for maintaining the pluripotency of chicken embryonic stem cells.
Kajihara R, Ezaki R, Ichikawa K, Watanabe T, Terada T, Matsuzaki M, Horiuchi H
Poultry science 2024 Feb;103(2):103361
Poultry science 2024 Feb;103(2):103361
Effect of Jiedu Huayu decoction on oral mucosal Axin and β-catenin expression in oral submucosal fibrosis model rats.
Xuan Z, An L, Keke Z, Mingyu R
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):688-693
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Aug;44(4):688-693
XAV-939 inhibits epithelial-mesenchymal transformation in pulmonary fibrosis induced by crystalline silica via the Wnt signaling pathway.
Lv Z, Xu H, Si X, Xu S, Li X, Li N, Zhou Q, Chang M, Yao S, Li H
Environmental toxicology 2023 Feb;38(2):460-471
Environmental toxicology 2023 Feb;38(2):460-471
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Zhou C, Zhu X, Liu N, Dong X, Zhang X, Huang H, Tang Y, Liu S, Hu M, Wang M, Deng X, Li S, Zhang R, Huang Y, Lyu H, Xiao S, Luo S, Ali DW, Michalak M, Chen XZ, Wang Z, Tang J
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Signal transduction and targeted therapy 2023 Feb 17;8(1):66
Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β.
Chen LJ, Wu L, Wang W, Zhai LL, Xiang F, Li WB, Tang ZG
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
SAC3D1 activates Wnt/β‑catenin signalling in hepatocellular carcinoma.
Wang H, Shi X
Molecular medicine reports 2022 Oct;26(4)
Molecular medicine reports 2022 Oct;26(4)
Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells.
Luo F, Li J, Liu J, Liu K
Cancer gene therapy 2022 Nov;29(11):1707-1719
Cancer gene therapy 2022 Nov;29(11):1707-1719
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Wei P, Jiang J, Xiao M, Zeng M, Liu X, Zhao B, Chen F
Experimental cell research 2022 Mar 1;412(1):113009
Experimental cell research 2022 Mar 1;412(1):113009
YTHDF2 interference suppresses the EMT of cervical cancer cells and enhances cisplatin chemosensitivity by regulating AXIN1.
Wu M, Chen G, Liao X, Xiao L, Zheng J
Drug development research 2022 Aug;83(5):1190-1200
Drug development research 2022 Aug;83(5):1190-1200
Targeting TRIM54/Axin1/β-Catenin Axis Prohibits Proliferation and Metastasis in Hepatocellular Carcinoma.
Zhu J, Wu Y, Lao S, Shen J, Yu Y, Fang C, Zhang N, Li Y, Zhang R
Frontiers in oncology 2021;11:759842
Frontiers in oncology 2021;11:759842
AXIN2 Reduces the Survival of Porcine Induced Pluripotent Stem Cells (piPSCs).
Zhang R, Yu S, Shen Q, Zhao W, Zhang J, Wu X, Zhu Z, Wu X, Li N, Peng S, Hua J
International journal of molecular sciences 2021 Nov 30;22(23)
International journal of molecular sciences 2021 Nov 30;22(23)
Tankyrase-1-mediated degradation of Golgin45 regulates glycosyltransferase trafficking and protein glycosylation in Rab2-GTP-dependent manner.
Yue X, Tiwari N, Zhu L, Ngo HDT, Lim JM, Gim B, Jing S, Wang Y, Qian Y, Lee I
Communications biology 2021 Dec 7;4(1):1370
Communications biology 2021 Dec 7;4(1):1370
A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway.
Ni D, Liu J, Hu Y, Liu Y, Gu Y, Zhou Q, Xie Y
In vitro cellular & developmental biology. Animal 2019 Apr;55(4):252-259
In vitro cellular & developmental biology. Animal 2019 Apr;55(4):252-259
Exosomes derived from mineralizing osteoblasts promote ST2 cell osteogenic differentiation by alteration of microRNA expression.
Cui Y, Luan J, Li H, Zhou X, Han J
FEBS letters 2016 Jan;590(1):185-92
FEBS letters 2016 Jan;590(1):185-92
HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.
Zha L, Zhang J, Tang W, Zhang N, He M, Guo Y, Wang Z
Digestive diseases and sciences 2013 Mar;58(3):724-33
Digestive diseases and sciences 2013 Mar;58(3):724-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AXIN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AXIN1. This antibody recognizes human, mouse, rat antigen. The AXIN1 antibody has been validated for the following applications: ELISA, WB analysis.
