AXIN1

gene product
PPP1R49
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
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498 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
152 antibodies
Novus Biologicals
7 antibodies
Cell Signaling Technology, Inc
3 antibodies
LifeSpan BioSciences, Inc.
112 antibodies
Invitrogen Antibodies
9 antibodies
Abnova Corporation
4 antibodies
R&D Systems
1 antibody
Acris Antibodies GmbH
9 antibodies
NovoPro Bioscience Inc.
6 antibodies
Abgent
5 antibodies
Biorbyt
59 antibodies
Proteintech Group
1 antibody
OriGene
6 antibodies
NSJ Bioreagents
3 antibodies
Aviva Systems Biology
5 antibodies
St John's Laboratory
3 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
Creative Biolabs
9 antibodies
GeneTex
3 antibodies
MyBioSource
10 antibodies
Creative Diagnostics
5 antibodies
Arigo
1 antibody
Bioworld Technology, Inc
1 antibody
Abiocode, Inc.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Signalway Antibody LLC
1 antibody
United States Biological
51 antibodies
EMD Millipore
4 antibodies
RayBiotech, Inc.
2 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
3 antibodies