Tissue expression
Cell line expression

AXIN1

gene product
PPP1R49 
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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572 antibodies from 40 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
152 antibodies
Proteintech Group
1 antibody
Novus Biologicals
7 antibodies
LifeSpan BioSciences, Inc.
152 antibodies
Cell Signaling Technology, Inc
3 antibodies
Invitrogen Antibodies
11 antibodies
Abnova Corporation
4 antibodies
Acris Antibodies GmbH
9 antibodies
Boster Biological Technology
1 antibody
R&D Systems
1 antibody
NovoPro Bioscience Inc.
6 antibodies
Abgent
5 antibodies
Biorbyt
59 antibodies
OriGene
6 antibodies
NSJ Bioreagents
3 antibodies
Aviva Systems Biology
5 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Everest Biotech
1 antibody
GeneTex
3 antibodies
MyBioSource
10 antibodies
Creative Diagnostics
6 antibodies
St John's Laboratory
3 antibodies
Arigo
1 antibody
Bioworld Technology, Inc
1 antibody
Leading Biology
6 antibodies
Creative Biolabs
9 antibodies
Abiocode, Inc.
1 antibody
Signalway Antibody LLC
1 antibody
United States Biological
51 antibodies
Abbexa
17 antibodies
EMD Millipore
4 antibodies
RayBiotech, Inc.
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Rockland Immunochemicals, Inc.
1 antibody