12153-1-AP

antibody from Proteintech Group

Targeting: USP18

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

12153-1-AP

Provider

Proteintech Group

Product name

USP18 antibody

Antibody type

Polyclonal

Description

USP18 antibody (Cat. #12153-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

ISG15 deficiency in hepatic stellate cells promotes TGFβ2-induced liver fibrosis by counteracting CREB1 ISGylation.

Yuan Y, Li J, Rao D, Lu X, Chen M, Chen X, Long X, Zhang B, Liang H, Chen Q, Zhao J
Gut 2026 May 12;75(6):1186-1200

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Porcine USP18 inhibits Japanese encephalitis virus replication by regulating the type I interferon signaling pathway.

Shi H, Li X, Zhou X, Wang H, Qin W, Jin H, Zhao A, Yang S
Veterinary microbiology 2026 Apr;315:110936

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USP18 promote tumor immune evasion in pancreatic cancer through enhancing autolysosome-mediated degradation of MHC-I.

Fang Y, Wang J, Fu B, Yu Y, Mao Q, Yao M, Yu X, Cai J
American journal of cancer research 2025;15(11):4999-5013

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USP18 Confers Paclitaxel Resistance in Non-Small Cell Lung Cancer by Stabilizing SHANK1 Expression Via Deubiquitination.

Chai L, Sun Y, Wang Y, Zhao C
Journal of biochemical and molecular toxicology 2025 Mar;39(3):e70197

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USP18 promotes ferroptosis in lipopolysaccharide-induced human kidney organoids by stabilizing STING1.

Yang H, Zhao L, Kong W, Liu S, Zhou Q, Lang X, Lan L, Wang Y
Cell biology and toxicology 2025 Aug 20;41(1):126

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Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.

Wang F, Amona FM, Pang Y, Zhang Q, Liang Y, Chen X, Ke Y, Chen J, Song C, Wang Y, Li Z, Zhang C, Fang X, Chen X
Journal of virology 2025 Apr 15;99(4):e0158524

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USP18 promotes the proliferation, invasion, and migration of head and neck squamous cell carcinoma by deubiquitinating PLK1.

Geng L, Liu F, Yang L, Liu Y, Wu G
Experimental cell research 2024 Oct 1;442(2):114284

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Adipose stem cell exosomes, stimulated by pro-inflammatory factors, enhance immune evasion in triple-negative breast cancer by modulating the HDAC6/STAT3/PD-L1 pathway through the transporter UCHL1.

Zhu Q, Zhang K, Cao Y, Hu Y
Cancer cell international 2024 Nov 20;24(1):385

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MiR-4769-3p suppresses adipogenesis in systemic sclerosis by negatively regulating the USP18/VDAC2 pathway.

Tang B, Yu J, Tang R, He X, Liu J, Liu L, Song Z, Shi Y, Zeng Z, Zhan Y, Qiu X, Xiao Y, Ding Y, Xiao R
iScience 2024 Aug 16;27(8):110483