ABIN401252

antibody from antibodies-online

Targeting: USP18

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN401252

Provider

antibodies-online

Product name

anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 40-49) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding aa 40-49 of human UBP43 protein

Description

Immunoaffinity chromatography

Reactivity

Human

Host

Rabbit

Epitope

AA 40-49

Isotype

IgG

Vial size

0.1 mg

Concentration

0.9 mg/mL (by UV absorbance at 280 nm)

Storage

Store the antibody at 2 - 8°C up to one month or for longer (in aliquots) at -20°C or below.

Handling

Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

References

Submitted references

The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase.

Tokarz S, Berset C, La Rue J, Friedman K, Nakayama K, Nakayama K, Zhang DE, Lanker S
The Journal of biological chemistry 2004 Nov 5;279(45):46424-30

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Human and mouse proteases: a comparative genomic approach.

Puente XS, Sánchez LM, Overall CM, López-Otín C
Nature reviews. Genetics 2003 Jul;4(7):544-58

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RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response.

Li XL, Blackford JA, Judge CS, Liu M, Xiao W, Kalvakolanu DV, Hassel BA
The Journal of biological chemistry 2000 Mar 24;275(12):8880-8

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Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18).

Schwer H, Liu LQ, Zhou L, Little MT, Pan Z, Hetherington CJ, Zhang DE
Genomics 2000 Apr 1;65(1):44-52