14-0238-80

antibody from Invitrogen Antibodies
Targeting: FCER2 CD23, CD23A, CLEC4J, FCE2
Provider product page for 14-0238-80
Immunohistochemistry
Flow cytometry
Other assay

Antibody data

Product number
14-0238-80 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD23 Monoclonal Antibody (EBVCS2), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelets. Expression of CD23 is upregulated upon B cell activation, and soluble forms of the antigen have been reported to be biologically active. CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B cell activation. CD21 and the alpha subunit of CD11b and CD11c bind to CD23. Applications Reported: The EBVCS2 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. Applications Tested: The EBVCS2 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
EBVCS2
Vial size
25 µg
Concentration
0.5 mg/mL
Storage
4° C
FCER2 protein structure - 14-0238-80 shown in red.