FCER2

The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]

Description

Fc fragment of IgE receptor II

Protein family

Cancer-related genes, CD markers, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Protein evidence (Peptideatlas)

Chromosome

19:p13.2 (7688758 - 7702146)

Ensembl ID

ENSG00000104921  (ver. 98.38)

Orthologs

Mouse Fcer2a: ENSMUSG00000005540

UniProt

P06734

neXtProt

NX_P06734

Human splice variants
Mouse splice variants