MA5-14054

antibody from Invitrogen Antibodies

Targeting: FCER2 CD23, CD23A, CLEC4J, FCE2

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-14054

Provider

Invitrogen Antibodies

Product name

CD23 Monoclonal Antibody (1B12)

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

MA5-14054 targets CD23 in IHC (P) applications and shows reactivity with Human samples. The MA5-14054 immunogen is recombinant external domain of CD23 protein.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1B12

Vial size

500 µL

Concentration

Conc. Not Determined

Storage

4° C

References

Submitted references

A subset of low-grade B cell lymphomas with a follicular growth pattern but without a BCL2 translocation shows features suggestive of nodal marginal zone lymphoma.

van den Brand M, Balagué O, van Cleef PH, Groenen PJ, Hebeda KM, de Jong D, van Krieken JH
Journal of hematopathology 2016 Mar;9(1):3-8

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Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.

Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo LD, Patrizi O, Sozzani S, de Saint Basile G, Latour S, Pace D, Lonardi S, Facchetti F, Badolato R, Parolini S
PloS one 2013;8(11):e80131

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Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders.

Lorenzi L, Lonardi S, Petrilli G, Tanda F, Bella M, Laurino L, Rossi G, Facchetti F
Human pathology 2012 Feb;43(2):209-15

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Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma.

Vermi W, Lonardi S, Bosisio D, Uguccioni M, Danelon G, Pileri S, Fletcher C, Sozzani S, Zorzi F, Arrigoni G, Doglioni C, Ponzoni M, Facchetti F
The Journal of pathology 2008 Nov;216(3):356-64

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Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.

Smit LA, Hallaert DY, Spijker R, de Goeij B, Jaspers A, Kater AP, van Oers MH, van Noesel CJ, Eldering E
Blood 2007 Feb 15;109(4):1660-8

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Composite splenic marginal zone lymphoma and mantle cell lymphoma arising from 2 independent B-cell clones.

Lefebvre C, Fabre B, Vettier C, Rabin L, Florin A, Wang J, Gressin R, Jacob MC, Callanan M, Leroux D
Human pathology 2007 Apr;38(4):660-7

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Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma.

Vermi W, Facchetti F, Riboldi E, Heine H, Scutera S, Stornello S, Ravarino D, Cappello P, Giovarelli M, Badolato R, Zucca M, Gentili F, Chilosi M, Doglioni C, Ponzi AN, Sozzani S, Musso T
Blood 2006 Jan 15;107(2):454-62

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Diagnosis and prognosis of B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL) and mantle cell lymphoma (MCL).

Asaad NY, Abd El-Wahed MM, Dawoud MM
Journal of the Egyptian National Cancer Institute 2005 Dec;17(4):279-90

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Inflammatory pseudotumor of the spleen with EBV positivity: report of a case.

Oz Puyan F, Bilgi S, Unlu E, Yalcin O, Altaner S, Demir M, Cakir B
European journal of haematology 2004 Apr;72(4):285-91

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded human tonsil stained with CD23 antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of B lymphocytes and dendritic cells.