Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB120-16702 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB120-16702, RRID:AB_789088
- Product name
- Rabbit Monoclonal CD23/Fc epsilon RII Antibody
- Antibody type
- Monoclonal
- Description
- Tissue culture supernatant. This antibody recognizes CD23, a 45kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells. It is strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukemia and some cases of centroblastic/centrocytic lymphoma. This antibody cross reacts with Human.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.5 ml
- Storage
- Store at 4C.
Submitted references B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.
Griss J, Bauer W, Wagner C, Simon M, Chen M, Grabmeier-Pfistershammer K, Maurer-Granofszky M, Roka F, Penz T, Bock C, Zhang G, Herlyn M, Glatz K, Läubli H, Mertz KD, Petzelbauer P, Wiesner T, Hartl M, Pickl WF, Somasundaram R, Steinberger P, Wagner SN
Nature communications 2019 Sep 13;10(1):4186
Nature communications 2019 Sep 13;10(1):4186
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD23 Antibody (SP23) [NB120-16702] - Analysis of CD23 in human tonsil (FFPE) using NB120-16702 at 1:100 dilution.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD23/Fc epsilon RII Antibody (SP23) [NB120-16702] - Formalin fixed paraffin embedded human tonsil stained with CD23 antibody (NB120-16702).