CABT-B8912

antibody from Creative Diagnostics

Targeting: AMH MIS

No application information provided.

Antibody Data

Product number

CABT-B8912

Provider

Creative Diagnostics

Product name

Anti-AMH (mature region) polyclonal antibody

Antibody type

Polyclonal

Description

Anti-m°îllerian hormone (AMH) has gained widespread interest as an indicator of ovarian function and fertility. Serum levels serve as a biomarker for the relative size of a woman's ovarian reserve and have clinical importance in predicting the success of in vitro fertilization (IVF). AMH can also be used as a surrogate diagnostic marker of polycystic ovary syndrome in cases when ultrasonographic examination is not possible.The AMH gene encodes an inactive homodimer precursor of identical disulphide-linked 70-kDa glycoproteins divided into two regions: pro-AMH (or N-terminal) and a C-terminal domain (also called the "mature" region). For signaling activation and binding to the AMH Receptor II, these domains require cleavage to yield two separate homodimers that remain associated in a noncovalent complex. Current commercial assays for AMH use antibody pairs that recognize the mature region only, or both the pro-AMH and mature regions.

Reactivity

Human

Host

Chicken/Avian

Conjugate

Unconjugated

Isotype

IgY

Concentration

Absorbance at 280nm (E 0.1%=1.4)Acceptable Range: 0.75 ÿ 1.25 mg/mLTested Concentration: 0.82 mg/mL

Storage

Store at -20°C.