CARD6

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]

Description

caspase recruitment domain family member 6

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

5:p13.1 (40841308 - 40860175)

Ensembl ID

ENSG00000132357  (ver. 99.38)

Orthologs

Mouse Card6: ENSMUSG00000041849

UniProt

Q9BX69

neXtProt

NX_Q9BX69

Human splice variants
Mouse splice variants