BS1038

antibody from Bioworld Technology, Inc
Targeting: CARD6 CINCIN1
Provider product page for BS1038
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1038 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1038, RRID:AB_1663934
Product name
CARD6 (A2) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to the N-terminual of Human CARD6.
Description
Membrane-associated guanylate kinase (MAGUK) family members localize to the plasma membrane and function as molecular scaffolds for the assembly of multi-protein complexes. The MAGUK family includes several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1ÿ3) and the caspase-associated recruitment domain (CARD) proteins, CARD 6, CARD 8-12 and CARD 14. CARD 6 is a 311 amino acid protein that associates with microtubules and acts as a selective mediator of NF°ÙB activation. CARD 6 is structurally and functionally related to the superfamily of interferon (IFN)-inducible GTPases, a group that comprises host defense proteins which mediate cell-autonomous immunity. RICK, the receptorinteracting protein (RIP)-like interacting caspase-like apoptosis regulatory protein kinase, interacts with CARD 6 and targets it to aggresomes, regions of the cell where protein aggregates collect.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CARD6 protein structure - BS1038 shown in red.