MA1-80944

antibody from Invitrogen Antibodies

Targeting: ENG CD105, END, HHT1, ORW, ORW1

Flow cytometry (Recommended by provider)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

MA1-80944

Provider

Invitrogen Antibodies

Product name

CD105 Monoclonal Antibody (SN6), PE

Antibody type

Monoclonal

Antigen

Other

Description

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL. Mouse anti Human CD105 antibody, clone SN6 recognizes the human endoglin, also known as CD105. CD105 is a glycoprotein homodimer of approximately 95 kDa subunits expressed by endothelial cells, activated monocytes and some leukemia cells.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

SN6

Vial size

100 Tests

Concentration

Conc. Not Determined

Storage

4° C, store in dark, DO NOT FREEZE!

References

Submitted references

Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.

Sávio-Silva C, Soinski-Sousa PE, Simplício-Filho A, Bastos RMC, Beyerstedt S, Rangel ÉB
International journal of molecular sciences 2021 Feb 4;22(4)

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Peripheral blood-derived mesenchymal stem cells demonstrate immunomodulatory potential for therapeutic use in horses.

Longhini ALF, Salazar TE, Vieira C, Trinh T, Duan Y, Pay LM, Li Calzi S, Losh M, Johnston NA, Xie H, Kim M, Hunt RJ, Yoder MC, Santoro D, McCarrel TM, Grant MB
PloS one 2019;14(3):e0212642

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Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models.

Dourado KMC, Baik J, Oliveira VKP, Beltrame M, Yamamoto A, Theuer CP, Figueiredo CAV, Verneris MR, Perlingeiro RCR
Blood 2017 May 4;129(18):2526-2536

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Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells.

Li SJ, Luo Y, Zhang LM, Yang W, Zhang GG
Molecular medicine reports 2017 Mar;15(3):1313-1318

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Differentiation of mesenchymal stem cells from human amniotic fluid to vascular endothelial cells.

Tancharoen W, Aungsuchawan S, Pothacharoen P, Markmee R, Narakornsak S, Kieodee J, Boonma N, Tasuya W
Acta histochemica 2017 Mar;119(2):113-121

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Mesenchymal stem cells differentiated into chondrocyte-Like cells.

Narakornsak S, Poovachiranon N, Peerapapong L, Pothacharoen P, Aungsuchawan S
Acta histochemica 2016 May;118(4):418-29

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Susceptibility of human placenta derived mesenchymal stromal/stem cells to human herpesviruses infection.

Avanzi S, Leoni V, Rotola A, Alviano F, Solimando L, Lanzoni G, Bonsi L, Di Luca D, Marchionni C, Alvisi G, Ripalti A
PloS one 2013;8(8):e71412

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Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6.

Haruta Y, Seon BK
Proceedings of the National Academy of Sciences of the United States of America 1986 Oct;83(20):7898-902

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Fig 1 MSCs derived from horse peripheral blood expressed typical MSC markers and reduced lameness in horses with osteoarthritis. (A) Representative phenotype of MSC, gray line represents unstained cells; the red filled line represents cells stained with individual specific antibodies (CD105, CD146, CD90, CD73). (B) The AAEP lameness scale was used for grading lameness before and after six weeks. Autologous MSCs were injected intravenously in 24 horses and lameness was graded before and at 6 weeks following MSC infusion (p

Conjugate

Yellow dye