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gene product
CD105, END, HHT1, ORW, ORW1
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
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Antibodies

 

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Antibodypedia Validation Initiative

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Eligible for validation within AVI
2425 antibodies from 51 providers.

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Antibody
Invitrogen Antibodies
47 antibodies
antibodies-online
744 antibodies
Proteintech Group
3 antibodies
R&D Systems
33 antibodies
Novus Biologicals
245 antibodies
OriGene
119 antibodies
GeneTex
27 antibodies
Acris Antibodies GmbH
40 antibodies
Biorbyt
115 antibodies
Abnova Corporation
26 antibodies
ReliaTech GmbH
12 antibodies
LifeSpan BioSciences, Inc.
345 antibodies
Affinity Biosciences
3 antibodies
Boster Biological Technology
3 antibodies
Antibodies.com
10 antibodies
NSJ Bioreagents
7 antibodies
NovoPro Bioscience Inc.
14 antibodies
Abgent
10 antibodies
Atlas Antibodies
3 antibodies
St John's Laboratory
4 antibodies
HUABIO Research
1 antibody
BioLegend
31 antibodies
Aviva Systems Biology
11 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
ProSci
13 antibodies
Bioworld Technology, Inc
2 antibodies
Creative Biolabs
144 antibodies
Cell Signaling Technology, Inc
3 antibodies
Creative Diagnostics
36 antibodies
Abbexa
40 antibodies
EMD Millipore
5 antibodies
RabMAbs
4 antibodies
United States Biological
94 antibodies
STEMCELL Technologies Inc
10 antibodies
MyBioSource
25 antibodies
Absolute Antibody
5 antibodies
ABEOMICS Inc.
4 antibodies
Sino Biological Inc.
13 antibodies
GenWay
13 antibodies
Leading Biology
9 antibodies
Miltenyi Biotec
55 antibodies
Spring Bioscience
4 antibodies
Abbiotec
1 antibody
Abiocode, Inc.
1 antibody
Sigma-Aldrich
6 antibodies
eBioscience, An Affymetrix Company
11 antibodies
RayBiotech, Inc.
10 antibodies
Nordic BioSite
2 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody