Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7463 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-ENG Monoclonal antibody, clone NK8/29
- Antibody type
- Monoclonal
- Description
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
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