Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10-7570 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Endoglin Antibody
- Antibody type
- Monoclonal
- Description
- ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant Endogl
in protein (amino acids 43-287) was
used as the immunogen for this ant
ibody.- Isotype
- IgG
- Antibody clone number
- ABM46D3
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Endoglin. Anti-Endoglin antibody (Clone: ABM46D3) was tested at 4 µg/ml on (1) PANC-1 and (2) THP1 lysates.
- Protocol
- Protocol