AMM02219G

antibody from Leading Biology

Targeting: ENG CD105, END, HHT1, ORW, ORW1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02219G

Provider

Leading Biology

Product name

CD105 Antibody (clone 8A1)

Antibody type

Monoclonal

Description

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Reactivity

Human, Mouse, Rat, Canine, Simian

Host

Mouse

Antibody clone number

8A1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.