ZNF598

Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. [provided by RefSeq, Oct 2012]

Description

Zinc finger protein 598, E3 ubiquitin ligase

Tissue specificity

Low tissue specificity

Subcell location

Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

16 (1997654 - 2009821)

Ensembl ID

ENSG00000167962  (ver. 103.38)

Orthologs

Mouse Zfp598: ENSMUSG00000041130

UniProt

 

neXtProt

 

Human splice variants
Mouse splice variants

Protein structure