AKAP11

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]

Description

A-kinase anchoring protein 11

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

13 (42272152 - 42323261)

Ensembl ID

ENSG00000023516  (ver. 103.38)

Orthologs

Mouse Akap11: ENSMUSG00000022016

UniProt

Q9UKA4

neXtProt

NX_Q9UKA4

Human splice variants
Mouse splice variants

Protein structure