TRAF7

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding. [supplied by OMIM, Apr 2004]

Description

TNF receptor associated factor 7

Protein family

Cancer-related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

16:p13.3 (2155698 - 2178129)

Ensembl ID

ENSG00000131653  (ver. 98.38)

Orthologs

Mouse Traf7: ENSMUSG00000052752

UniProt

Q6Q0C0

neXtProt

NX_Q6Q0C0

Human splice variants
Mouse splice variants