Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11780-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- TRAF7 antibody
- Antibody type
- Polyclonal
- Description
- TRAF7 antibody (Cat. #11780-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references cba-miR-222-3p involved in photoperiod-induced apoptosis in testes of striped hamsters by targeting TRAF7.
Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 in Yotari (Dab1(-/-)) Mice: Implicationsfor Understanding CAKUT Pathogenesis.
Hypoxia-induced conversion of sensory Schwann cells into repair cells is regulated by HDAC8.
TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence.
Expression of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Candidate Genes EDA2R, PCDH9, and TRAF7 in Normal Human Kidney Development and CAKUT.
The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.
Cardiac tumour necrosis factor receptor-associated factor 7 mediates the ubiquitination of apoptosis signal-regulating kinase 1 and aggravates cardiac hypertrophy.
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.
TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1.
HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis.
Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney.
Wang S, Xu J, Wang X, Wang M, Xue H, Wu M, Fan C, Chen L, Xu L
Integrative zoology 2025 Jul;20(4):836-849
Integrative zoology 2025 Jul;20(4):836-849
Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 in Yotari (Dab1(-/-)) Mice: Implicationsfor Understanding CAKUT Pathogenesis.
Komić J, Kelam N, Racetin A, Filipović N, Saraga-Babić M, Ihara D, Katsuyama Y, Vukojević K
International journal of molecular sciences 2025 Jul 3;26(13)
International journal of molecular sciences 2025 Jul 3;26(13)
Hypoxia-induced conversion of sensory Schwann cells into repair cells is regulated by HDAC8.
Hertzog N, Duman M, Bochud M, Brügger-Verdon V, Gerhards M, Schön F, Dorndecker F, Meijer D, Fledrich R, Stassart R, Sankar DS, Dengjel J, López SR, Jacob C
Nature communications 2025 Jan 9;16(1):515
Nature communications 2025 Jan 9;16(1):515
TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence.
Chen Y, Zhou T, Zhou R, Sun W, Li Y, Zhou Q, Xu D, Zhao Y, Hu P, Liang J, Zhang Y, Zhong B, Yao J, Jing D
Journal of experimental & clinical cancer research : CR 2025 Apr 4;44(1):112
Journal of experimental & clinical cancer research : CR 2025 Apr 4;44(1):112
Expression of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Candidate Genes EDA2R, PCDH9, and TRAF7 in Normal Human Kidney Development and CAKUT.
Kelam J, Kelam N, Filipović N, Komić L, Racetin A, Komić D, Kostić S, Kuzmić Prusac I, Vukojević K
Genes 2024 May 28;15(6)
Genes 2024 May 28;15(6)
The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.
Song X, Hu R, Chen Y, Xiao M, Zhang H, Wu S, Lu Q
Journal of molecular cell biology 2024 Jul 1;16(1)
Journal of molecular cell biology 2024 Jul 1;16(1)
Cardiac tumour necrosis factor receptor-associated factor 7 mediates the ubiquitination of apoptosis signal-regulating kinase 1 and aggravates cardiac hypertrophy.
Che Y, Liu YT, Wang ZP, Feng YZ, Xia HX, Yuan Y, Zhou H, Qiu HL, Hu ML, Wang SS, Tang QZ
Cardiovascular research 2024 Dec 14;120(16):2031-2046
Cardiovascular research 2024 Dec 14;120(16):2031-2046
Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta.
Li Q, Kang J, Liu N, Huang J, Zhang X, Pang K, Zhang S, Wang M, Zhao Y, Dong S, Li H, Zhao D, Lu F, Zhang W
Free radical biology & medicine 2024 Apr;216:118-138
Free radical biology & medicine 2024 Apr;216:118-138
TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling.
Ye J, Liu W, Yu X, Wu L, Chen Z, Yu Y, Wang J, Bai S, Zhang M
Cell death discovery 2023 Oct 16;9(1):378
Cell death discovery 2023 Oct 16;9(1):378
TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1.
Huang JP, Yang YX, Chen T, Wang DD, Li J, Xu LG
Virologica Sinica 2023 Jun;38(3):419-428
Virologica Sinica 2023 Jun;38(3):419-428
HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis.
Zhang Z, Wen H, Peng B, Weng J, Zeng F
Molecular therapy. Nucleic acids 2021 Jun 4;24:711-727
Molecular therapy. Nucleic acids 2021 Jun 4;24:711-727
Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney.
Westland R, Verbitsky M, Vukojevic K, Perry BJ, Fasel DA, Zwijnenburg PJ, Bökenkamp A, Gille JJ, Saraga-Babic M, Ghiggeri GM, D'Agati VD, Schreuder MF, Gharavi AG, van Wijk JA, Sanna-Cherchi S
Kidney international 2015 Dec;88(6):1402-1410
Kidney international 2015 Dec;88(6):1402-1410
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-TRAF7 (IP:11780-1-AP, 3ug; Detection:11780-1-AP 1:300) with mouse liver tissue lysate 3000ug.
- Other comments
- IP
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11780-1-AP(TRAF7 antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC