BS6687

antibody from Bioworld Technology, Inc
Targeting: PDE4D DPDE3
Provider product page for BS6687
Western blot
Immunohistochemistry

Antibody data

Product number
BS6687 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PDE4D polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PDE4D.
Description
Phosphodiesterases (PDE) hydrolyze cAMP to 5£ªAMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4D gene maps to chromosome 5q11.2. The splice variants include isoforms PDE4D1-6.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PDE4D protein structure - BS6687 shown in red.