CENPB

gene product
This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008]
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Novus Biologicals
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Invitrogen Antibodies
3 antibodies
antibodies-online
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Abnova Corporation
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Biorbyt
7 antibodies
LifeSpan BioSciences, Inc.
13 antibodies
Atlas Antibodies
2 antibodies
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Aviva Systems Biology
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GeneTex
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Creative Diagnostics
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United States Biological
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Sigma-Aldrich
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EMD Millipore
1 antibody