PAB7414

antibody from Abnova Corporation

Targeting: ACVR1 ACVR1A, ACVRLK2, ALK2, SKR1

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB7414

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB7414, RRID:AB_1571112

Product name

ACVR1 polyclonal antibody

Antibody type

Polyclonal

Description

Goat polyclonal antibody raised against synthetic peptide of ACVR1.

Antigen sequence

C-RKFKRRNQERLNPRD


Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva.

Shore EM, Xu M, Feldman GJ, Fenstermacher DA, Cho TJ, Choi IH, Connor JM, Delai P, Glaser DL, LeMerrer M, Morhart R, Rogers JG, Smith R, Triffitt JT, Urtizberea JA, Zasloff M, Brown MA, Kaplan FS
Nature genetics 2006 May;38(5):525-7

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

ACVR1 polyclonal antibody (Cat # PAB7414) (0.3 ug/mL) staining of human umbilical cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

ACVR1 polyclonal antibody (4 ug/mL) staining of paraffin embedded human testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)