AIPL1

gene product
LCA4
Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
321 antibodies from 30 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
116 antibodies
Novus Biologicals
32 antibodies
Abnova Corporation
8 antibodies
OriGene
17 antibodies
GeneTex
4 antibodies
LifeSpan BioSciences, Inc.
33 antibodies
NovoPro Bioscience Inc.
4 antibodies
Invitrogen Antibodies
5 antibodies
Abgent
5 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Acris Antibodies GmbH
7 antibodies
Biorbyt
14 antibodies
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
St John's Laboratory
2 antibodies
Abbexa
1 antibody
RabMAbs
2 antibodies
MyBioSource
5 antibodies
Creative Biolabs
8 antibodies
RayBiotech, Inc.
3 antibodies
United States Biological
24 antibodies
Abbiotec
2 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
1 antibody
Boster Biological Technology
1 antibody
Creative Diagnostics
4 antibodies
Sigma-Aldrich
3 antibodies