Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1881186 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD46 Molecule, Complement Regulatory Protein (CD46) (Center), (Tyr354), (AA 330-361) antibody
- Antibody type
- Polyclonal
- Antigen
- This CD46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-361 amino acids from the Central region of human CD46.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,Tyr354,AA 330-361
- Vial size
- 400 μL
- Concentration
- 0.36 mg/mL
Submitted references Characterization of human membrane cofactor protein (MCP; CD46) on spermatozoa.
Characterization of a cDNA clone coding for human testis membrane cofactor protein (MCP, CD46).
Alternatively spliced RNAs encode several isoforms of CD46 (MCP), a regulator of complement activation.
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.
Riley RC, Kemper C, Leung M, Atkinson JP
Molecular reproduction and development 2002 Aug;62(4):534-46
Molecular reproduction and development 2002 Aug;62(4):534-46
Characterization of a cDNA clone coding for human testis membrane cofactor protein (MCP, CD46).
Cervoni F, Fenichel P, Akhoundi C, Hsi BL, Rossi B
Molecular reproduction and development 1993 Jan;34(1):107-13
Molecular reproduction and development 1993 Jan;34(1):107-13
Alternatively spliced RNAs encode several isoforms of CD46 (MCP), a regulator of complement activation.
Purcell DF, Russell SM, Deacon NJ, Brown MA, Hooker DJ, McKenzie IF
Immunogenetics 1991;33(5-6):335-44
Immunogenetics 1991;33(5-6):335-44
Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.
Post TW, Liszewski MK, Adams EM, Tedja I, Miller EA, Atkinson JP
The Journal of experimental medicine 1991 Jul 1;174(1):93-102
The Journal of experimental medicine 1991 Jul 1;174(1):93-102
Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.
Lublin DM, Liszewski MK, Post TW, Arce MA, Le Beau MM, Rebentisch MB, Lemons LS, Seya T, Atkinson JP
The Journal of experimental medicine 1988 Jul 1;168(1):181-94
The Journal of experimental medicine 1988 Jul 1;168(1):181-94
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- CD46 Antibody (Y354) (ABIN1881186) western blot analysis in A549,Hela cell line lysates (35 μg/lane). This demonstrates the CD46 antibody detected the CD46 protein (arrow).