CD46

gene product
MCP, MGC26544, MIC10, TLX, TRA2.10
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
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788 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
91 antibodies
Abgent
4 antibodies
antibodies-online
172 antibodies
Biorbyt
38 antibodies
NSJ Bioreagents
7 antibodies
OriGene
22 antibodies
Invitrogen Antibodies
16 antibodies
R&D Systems
12 antibodies
GeneTex
14 antibodies
Aviva Systems Biology
8 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Acris Antibodies GmbH
21 antibodies
LifeSpan BioSciences, Inc.
160 antibodies
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
Antibodies.com
6 antibodies
Boster Biological Technology
5 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
12 antibodies
BioLegend
17 antibodies
Santa Cruz Biotechnology
1 antibody
Arigo
6 antibodies
MyBioSource
15 antibodies
St John's Laboratory
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Cell Signaling Technology, Inc
1 antibody
Creative Diagnostics
9 antibodies
RabMAbs
2 antibodies
United States Biological
39 antibodies
Sino Biological Inc.
5 antibodies
Creative Biolabs
56 antibodies
Abbexa
12 antibodies
GenWay
7 antibodies
RayBiotech, Inc.
2 antibodies
Sigma-Aldrich
2 antibodies
eBioscience, An Affymetrix Company
2 antibodies