Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B12158 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Human anti-Human MPL recombinant monoclonal antibody, clone SFB360 [PE]
- Antibody type
- Monoclonal
- Description
- It recognozes the CD110 antigen, a type I transmembrane protein and a member of the hematopoietin receptor family, which is also known as myeloproliferative leukemia protein (MPL) or thrombopoietin receptor (TPO-R). CD110 is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets. It serves as a receptor for thrombopoietin and CD110 deficiency leads to severe thrombocytopenia, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Additional information: It displays negligible binding to Fc receptors.
- Reactivity
- Human
- Host
- Human
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- SFB360
- Vial size
- for 100 tests
- Storage
- Store protected from light at 2ÿ8 °C. Do not freeze.
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