RCBTB1

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]

Description

RCC1 and BTB domain containing protein 1

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

13:q14.2 (49531946 - 49585558)

Ensembl ID

ENSG00000136144  (ver. 99.38)

Orthologs

Mouse Rcbtb1: ENSMUSG00000035469

UniProt

Q8NDN9

neXtProt

NX_Q8NDN9

Human splice variants
Mouse splice variants