14845-1-AP

antibody from Proteintech Group

Targeting: CRLS1 C20orf155, CLS1, dJ967N21.6, GCD10

Provider product page for 14845-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [11]
Comments [0]
Validations
Immunohistochemistry [2]

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Product number: 14845-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14845-1-AP, RRID:AB_2085336
Product name: CRLS1-Specific antibody
Antibody type: Polyclonal
Description: KD/KO validated CRLS1-Specific antibody (Cat. #14845-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CRLS1 protein structure - 14845-1-AP shown in red.

Submitted references SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.

Liu LX, Zheng XH, Hai JH, Zhang CM, Ti Y, Chen TS, Bu PL
PloS one 2024;19(4):e0301990

Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.

Yang D, Li J, Li Z, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
Frontiers in molecular neuroscience 2023;16:1163981

Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation.

Gong H, Ma C, Li X, Zhang X, Zhang L, Chen P, Wang W, Hu Y, Huang T, Wu N, Wang X
Frontiers in bioscience (Landmark edition) 2023 May 11;28(5):89

Cristae formation is a mechanical buckling event controlled by the inner mitochondrial membrane lipidome.

Venkatraman K, Lee CT, Garcia GC, Mahapatra A, Milshteyn D, Perkins G, Kim KY, Pasolli HA, Phan S, Lippincott-Schwartz J, Ellisman MH, Rangamani P, Budin I
The EMBO journal 2023 Dec 11;42(24):e114054

Exercise and Doxorubicin Modify Markers of Iron Overload and Cardiolipin Deficiency in Cardiac Mitochondria.

Montalvo RN, Boeno FP, Dowllah IM, Moritz CEJ, Nguyen BL, Doerr V, Bomkamp MP, Smuder AJ
International journal of molecular sciences 2023 Apr 22;24(9)

Exercise ameliorates high-fat diet-induced insulin resistance accompanied by changes in protein levels of hepatic ATF3-related signaling in rats.

Yang Z, Huang G, Zhou P, Zhang Y, Ding J, Sun Q, Hua T
Physiology & behavior 2022 May 15;249:113766

Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms.

Khan M, Qiao F, Kumar P, Touhidul Islam SM, Singh AK, Won J, Singh I
Neural regeneration research 2022 Jan;17(1):185-193

Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.

Wu L, Guo X, Wong SY, Lu P, Hartson SD, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Lin D
The Journal of nutritional biochemistry 2021 Feb;88:108542

Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells.

Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S
Biochimica et biophysica acta 2016 Apr;1857(4):443-53

Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia.

Peyta L, Jarnouen K, Pinault M, Coulouarn C, Guimaraes C, Goupille C, de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S
Biochimica et biophysica acta 2015 Nov;1851(11):1490-500

Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency.

Kiebish MA, Yang K, Sims HF, Jenkins CM, Liu X, Mancuso DJ, Zhao Z, Guan S, Abendschein DR, Han X, Gross RW
The Journal of biological chemistry 2012 Jul 20;287(30):25086-97

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The CRLS1-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CRLS1-Specific. This antibody recognizes human, mouse, rat antigen. The CRLS1-Specific antibody has been validated for the following applications: ELISA, IHC analysis.
Appendix: 14845-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human liver cancer using 14845-1-AP(CRLS1-Specific antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue