Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- GTX117446 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX117446, RRID:AB_10615812
- Product name
- PD-L1 antibody [N1C2]
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein encompassing a sequence within the center region of human PD-L1. The exact sequence is proprietary.
- Reactivity
- Bovine, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25µl, 100µl
- Concentration
- 1 mg/ml
- Storage
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Submitted references Predictive value of PD-L1 based on mRNA level in the treatment of stage IV melanoma with ipilimumab.
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
Brüggemann C, Kirchberger MC, Goldinger SM, Weide B, Konrad A, Erdmann M, Schadendorf D, Croner RS, Krähenbühl L, Kähler KC, Hafner C, Leisgang W, Kiesewetter F, Dummer R, Schuler G, Stürzl M, Heinzerling L
Journal of cancer research and clinical oncology 2017 Oct;143(10):1977-1984
Journal of cancer research and clinical oncology 2017 Oct;143(10):1977-1984
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
Li CW, Lim SO, Xia W, Lee HH, Chan LC, Kuo CW, Khoo KH, Chang SS, Cha JH, Kim T, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Ding Q, Wang Y, Yao J, Lee CC, Wu HJ, Sahin AA, Allison JP, Yu D, Hortobagyi GN, Hung MC
Nature communications 2016 Aug 30;7:12632
Nature communications 2016 Aug 30;7:12632
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE GTX117446 diluted at 1:1000
- Validation comment
- WB