28076-1-AP
antibody from Proteintech Group
Targeting: CD274
B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1
Antibody data
- Antibody Data
- Antigen structure
- References [86]
- Comments [0]
- Validations [0]
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- Product number
- 28076-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PD-L1/CD274 (C-terminal) antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PD-L1/CD274 (C-terminal) antibody (Cat. #28076-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.
Coactosin-Like Protein 1 (COTL1) Could Be an Immunological and Prognostic Biomarker: From Pan-Cancer Analysis to Low-Grade Glioma Validation.
Construction of disulfidptosis-based immune response prediction model with artificial intelligence and validation of the pivotal grouping oncogene c-MET in regulating T cell exhaustion.
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
lncRNA MIAT promotes luminal B breast cancer cell proliferation, migration, and invasion in vitro.
Icaritin-curcumol activates CD8(+) T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer.
Aptamer-bivalent-cholesterol-mediated proximity entropy-driven exosomal protein reporter for tumor diagnosis.
DEAD-box helicase 1 inhibited CD8(+) T cell antitumor activity by inducing PD-L1 expression in hepatocellular carcinoma.
GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
An innovative nanoformulation utilizing tumor microenvironment-responsive PEG-polyglutamic coating and dynamic charge adjustment for specific targeting of ER stress inducer, microRNA, and immunoadjuvant in pancreatic cancer: In vitro investigations.
Bioinformatics Analysis Identifies PLA2G7 as a Key Antigen-Presenting Prognostic Related Gene Promoting Hepatocellular Carcinoma through the STAT1/PD-L1 Axis.
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
MT1G, an emerging ferroptosis-related gene: A novel prognostic biomarker and indicator of immunotherapy sensitivity in prostate cancer.
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3.
Proton-Gradient-Driven Porphyrin-Based Liposome Remote-Loaded with Imiquimod as In Situ Nanoadjuvants for Synergistically Augmented Tumor Photoimmunotherapy.
Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3.
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma.
S100A9 Induces Macrophage M2 Polarization and Immunomodulatory Role in the Lesion Site After Spinal Cord Injury in Rats.
GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.
Tackling Esophageal Squamous Cell Carcinoma with ITFn-Pt(IV): A Novel Fusion of PD-L1 Blockade, Chemotherapy, and T-cell Activation.
Ginger inhibits the invasion of ovarian cancer cells SKOV3 through CLDN7, CLDN11 and CD274 m6A methylation modifications.
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression.
Prognostic biomarker DARS2 correlated with immune infiltrates in bladder tumor.
Overexpression of DBT suppresses the aggressiveness of renal clear cell carcinoma and correlates with immune infiltration.
Machine learning-based identification of tumor-infiltrating immune cell-associated model with appealing implications in improving prognosis and immunotherapy response in bladder cancer patients.
LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma.
A prognostic signature based on snoRNA predicts the overall survival of lower-grade glioma patients.
Discovery of CDK signature and CDK5 as potential biomarkers for predicting prognosis and immunotherapeutic response in gastric cancer peritoneal metastases.
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas.
Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma.
Construction and Evaluation of Novel Dual-function Antifungal Inhibitors and Covalent Organic Framework Carriers Based on the Infection Microenvironment.
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Electroacupuncture Alleviates CFA-Induced Inflammatory Pain via PD-L1/PD-1-SHP-1 Pathway.
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer.
PD-L1 Exon 3 Is a Hidden Switch of Its Expression and Function in Oral Cancer Cells.
Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental analysis.
ZNF480 influences the prognosis, pathogenesis, and immune microenvironment in patients with lower-grade glioma.
Increased OIT3 in macrophages promotes PD-L1 expression and hepatocellular carcinogenesis via NF-κB signaling.
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53(flox/+)LSL-Kras(G12D/+)Pdx-1-Cre murine models.
Inhibition of ACLY overcomes cancer immunotherapy resistance via polyunsaturated fatty acids peroxidation and cGAS-STING activation.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Relationship between the expression of PD-L1 and (18)F-FDG uptake in pancreatic ductal adenocarcinoma.
m(6)A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.
Biosynthesized gold nanoparticles that activate Toll-like receptors and elicit localized light-converting hyperthermia for pleiotropic tumor immunoregulation.
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
The role of YAP1 in survival prediction, immune modulation, and drug response: A pan-cancer perspective.
Bacteria-mediated metformin-loaded peptide hydrogel reprograms the tumor immune microenvironment in glioblastoma.
Multimodal Imaging Response after the Singular or Combination Treatments of Vascular Endothelial Growth Factor Inhibitor and Immune Checkpoint Inhibitor.
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade.
BMSCs improve TNBS-induced colitis in rats by inducing Treg differentiation by expressing PD-L1.
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients.
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Comprehensive analysis of N(6)-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer.
Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment.
Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy.
Berry anthocyanidins inhibit intestinal polyps and colon tumors by modulation of Src, EGFR and the colon inflammatory environment.
IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study.
c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis.
What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 1: Focus on Immunohistochemical Results with Discussion of Pre-Analytical and Interpretation Variables.
Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
Identification and validation of a combined hypoxia and immune index for triple-negative breast cancer.
Tumor-associated macrophages induce PD-L1 expression in gastric cancer cells through IL-6 and TNF-ɑ signaling.
New insight on the correlation of metabolic status on (18)F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer.
Anti-PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells.
An update of knowledge on PD-L1 in head and neck cancers: Physiologic, prognostic and therapeutic perspectives.
Changes in Tumor-Infiltrating Lymphocytes and Vascular Normalization in Breast Cancer Patients After Neoadjuvant Chemotherapy and Their Correlations With DFS.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
All-trans retinoic acid induces anti-tumor effects via STAT3 signaling inhibition in oral squamous cell carcinoma and oral dysplasia.
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
PD-1 Blockade Following Isolated Limb Perfusion with Vaccinia Virus Prevents Local and Distant Relapse of Soft-tissue Sarcoma.
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Hyperresponsiveness to interferon gamma exposure as a response mechanism to anti-PD-1 therapy in microsatellite instability colorectal cancer.
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
The prognostic role of PD-L1 expression for survival in head and neck squamous cell carcinoma: A systematic review and meta-analysis.
Programmed death-ligand 1 (PD-L1) expression in pleomorphic carcinoma of the lung.
The expression of PD-L1 protein as a prognostic factor in lung squamous cell carcinoma.
Associations among pretreatment tumor necrosis and the expression of HIF-1α and PD-L1 in advanced oral squamous cell carcinoma and the prognostic impact thereof.
Zhang F, Zhou K, Yuan W, Sun K
Nutrition and cancer 2024;76(1):63-79
Nutrition and cancer 2024;76(1):63-79
Coactosin-Like Protein 1 (COTL1) Could Be an Immunological and Prognostic Biomarker: From Pan-Cancer Analysis to Low-Grade Glioma Validation.
Wang X, Bai Y, Wang B
Journal of inflammation research 2024;17:1805-1820
Journal of inflammation research 2024;17:1805-1820
Construction of disulfidptosis-based immune response prediction model with artificial intelligence and validation of the pivotal grouping oncogene c-MET in regulating T cell exhaustion.
Li P, Wang S, Wan H, Huang Y, Yin K, Sun K, Jin H, Wang Z
Frontiers in immunology 2024;15:1258475
Frontiers in immunology 2024;15:1258475
Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma.
Liang Y, He S, Liu Q, Liu T, Tan Y, Peng T, Huang C, Lu X, Zheng S
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119781
lncRNA MIAT promotes luminal B breast cancer cell proliferation, migration, and invasion in vitro.
Mi J, Zhang H, Jiang X, Yi Y, Cao W, Song C, Yuan C
Journal of applied genetics 2024 May;65(2):309-319
Journal of applied genetics 2024 May;65(2):309-319
Icaritin-curcumol activates CD8(+) T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer.
Xu W, Li Y, Liu L, Xie J, Hu Z, Kuang S, Fu X, Li B, Sun T, Zhu C, He Q, Sheng W
Journal of experimental & clinical cancer research : CR 2024 May 23;43(1):149
Journal of experimental & clinical cancer research : CR 2024 May 23;43(1):149
Aptamer-bivalent-cholesterol-mediated proximity entropy-driven exosomal protein reporter for tumor diagnosis.
Fan Z, Zhou J, Shu Q, Dong Y, Li Y, Zhang T, Bai G, Yu H, Lu F, Li J, Zhao X
Biosensors & bioelectronics 2024 May 1;251:116104
Biosensors & bioelectronics 2024 May 1;251:116104
DEAD-box helicase 1 inhibited CD8(+) T cell antitumor activity by inducing PD-L1 expression in hepatocellular carcinoma.
Liu J, Yang T, Luo Y, Ma Z, Yu Z, Zhang L, Liu G, Wen J, Lu G, Zhang G, Zhao Y, Luo W, Li Y, Yang N, Zhou J, Lu Y, Chen S, Zeng X
Cancer science 2024 Mar;115(3):763-776
Cancer science 2024 Mar;115(3):763-776
GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Khan B, Chen M, Wang H, Khan A, Hussain S, Shi J, Yang L, Hou Y
European journal of pharmacology 2024 Jun 5;972:176565
European journal of pharmacology 2024 Jun 5;972:176565
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Zhang J, Xin Y, Ling X, Liang H, Zhang L, Fang C, Ma J
Human cell 2024 Jan;37(1):245-257
Human cell 2024 Jan;37(1):245-257
An innovative nanoformulation utilizing tumor microenvironment-responsive PEG-polyglutamic coating and dynamic charge adjustment for specific targeting of ER stress inducer, microRNA, and immunoadjuvant in pancreatic cancer: In vitro investigations.
Li CY, Chou TF, Lo YL
International journal of biological macromolecules 2024 Jan;254(Pt 2):127905
International journal of biological macromolecules 2024 Jan;254(Pt 2):127905
Bioinformatics Analysis Identifies PLA2G7 as a Key Antigen-Presenting Prognostic Related Gene Promoting Hepatocellular Carcinoma through the STAT1/PD-L1 Axis.
Guo S, Yang Q
Frontiers in bioscience (Landmark edition) 2024 Jan 23;29(1):39
Frontiers in bioscience (Landmark edition) 2024 Jan 23;29(1):39
The tertiary lymphoid structure-related signature identified PTGDS in regulating PD-L1 and promoting the proliferation and migration of glioblastoma.
Wu W, Li H, Wang Z, Dai Z, Liang X, Luo P, Liu K, Zhang H, Zhang N, Li S, Zhang C
Heliyon 2024 Jan 15;10(1):e23915
Heliyon 2024 Jan 15;10(1):e23915
MT1G, an emerging ferroptosis-related gene: A novel prognostic biomarker and indicator of immunotherapy sensitivity in prostate cancer.
Cheng B, Lai Y, Huang H, Peng S, Tang C, Chen J, Luo T, Wu J, He H, Wang Q, Huang H
Environmental toxicology 2024 Feb;39(2):927-941
Environmental toxicology 2024 Feb;39(2):927-941
The Identification of Gamma-Glutamyl Hydrolase in Uterine Corpus Endometrial Carcinoma: a Predictive Model and Machine Learning.
Zhu C, Du Y, Huai Q, Fang N, Xu W, Yang J, Li X, Zhang Y, Zhang X, Dai H, Li X, Wang H, Dai Y
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
Reproductive sciences (Thousand Oaks, Calif.) 2024 Feb;31(2):532-549
A pan-cancer analysis of prognostic significance and immunological role of lysosomal-associated membrane protein 3.
Feng X, Gao L, Shen X, Li M, Wang X, Hao Y, Chen J, Zhai Y, Zou B, Yao S, Guo Y, Zhang L
Journal of cellular and molecular medicine 2024 Feb;28(3):e18088
Journal of cellular and molecular medicine 2024 Feb;28(3):e18088
Proton-Gradient-Driven Porphyrin-Based Liposome Remote-Loaded with Imiquimod as In Situ Nanoadjuvants for Synergistically Augmented Tumor Photoimmunotherapy.
Liu D, Fu L, Gong L, Li S, Li K, Liu K, Yang D
ACS applied materials & interfaces 2024 Feb 21;16(7):8403-8416
ACS applied materials & interfaces 2024 Feb 21;16(7):8403-8416
Benzosceptrin C induces lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting DHHC3.
Wang Q, Wang J, Yu D, Zhang Q, Hu H, Xu M, Zhang H, Tian S, Zheng G, Lu D, Hu J, Guo M, Cai M, Geng X, Zhang Y, Xia J, Zhang X, Li A, Liu S, Zhang W
Cell reports. Medicine 2024 Feb 20;5(2):101357
Cell reports. Medicine 2024 Feb 20;5(2):101357
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Liu Y, He J, Li M, Ren K, Zhao Z
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
TLR9 activation induces immunosuppression and tumorigenesis via PARP1/PD-L1 signaling pathway in oral squamous cell carcinoma.
Ma L, Qin N, Wan W, Song S, Hua S, Jiang C, Li N, Huang L, Gao X
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C362-C381
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C362-C381
S100A9 Induces Macrophage M2 Polarization and Immunomodulatory Role in the Lesion Site After Spinal Cord Injury in Rats.
Lv J, Wang Z, Wang B, Deng C, Wang W, Sun L
Molecular neurobiology 2024 Aug;61(8):5525-5540
Molecular neurobiology 2024 Aug;61(8):5525-5540
GHITM regulates malignant phenotype and sensitivity to PD-1 blockade of renal cancer cells via Notch signalling.
Huang S, Liu J, Hu J, Hou Y, Hu M, Zhang B, Luo H, Fu S, Chen Y, Liu X, Chen Z, Wang L
Journal of cellular and molecular medicine 2024 Apr;28(8):e18290
Journal of cellular and molecular medicine 2024 Apr;28(8):e18290
Tackling Esophageal Squamous Cell Carcinoma with ITFn-Pt(IV): A Novel Fusion of PD-L1 Blockade, Chemotherapy, and T-cell Activation.
Xin Q, Wang D, Wang S, Zhang L, Liang Q, Yan X, Fan K, Jiang B
Advanced healthcare materials 2024 Apr;13(11):e2303623
Advanced healthcare materials 2024 Apr;13(11):e2303623
Ginger inhibits the invasion of ovarian cancer cells SKOV3 through CLDN7, CLDN11 and CD274 m6A methylation modifications.
Zhang X, Zhang H, Zhu L, Xia L
BMC complementary medicine and therapies 2024 Apr 4;24(1):145
BMC complementary medicine and therapies 2024 Apr 4;24(1):145
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression.
Cui Z, Li C, Liu W, Sun M, Deng S, Cao J, Yang H, Chen P
Cell death & disease 2024 Apr 15;15(4):267
Cell death & disease 2024 Apr 15;15(4):267
Prognostic biomarker DARS2 correlated with immune infiltrates in bladder tumor.
Yang H, Ma L, Deng W, Fu B, Nie J, Liu X
Frontiers in immunology 2023;14:1301945
Frontiers in immunology 2023;14:1301945
Overexpression of DBT suppresses the aggressiveness of renal clear cell carcinoma and correlates with immune infiltration.
Zhang C, Huang G, Yang J, Jiang Y, Huang R, Ye Z, Huang Y, Hu H, Xi X
Frontiers in immunology 2023;14:1197011
Frontiers in immunology 2023;14:1197011
Machine learning-based identification of tumor-infiltrating immune cell-associated model with appealing implications in improving prognosis and immunotherapy response in bladder cancer patients.
Chen H, Yang W, Ji Z
Frontiers in immunology 2023;14:1171420
Frontiers in immunology 2023;14:1171420
LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma.
Wang H, Tang A, Cui Y, Gong H, Li H
Frontiers in immunology 2023;14:1144774
Frontiers in immunology 2023;14:1144774
A prognostic signature based on snoRNA predicts the overall survival of lower-grade glioma patients.
Zhou Y, Yin W, Kuang Y, Wu Z, Huang H, Liu W, Jiang X, Ren C
Frontiers in immunology 2023;14:1138363
Frontiers in immunology 2023;14:1138363
Discovery of CDK signature and CDK5 as potential biomarkers for predicting prognosis and immunotherapeutic response in gastric cancer peritoneal metastases.
Sun Y, Chen Y, Cai Y, Wang X, Chen Q, Fang S, Lian M, Lv C, Weng J, Huang R, Zhuang W, Xue F, Cai L, Lin Y, Wang Q
American journal of cancer research 2023;13(9):4087-4100
American journal of cancer research 2023;13(9):4087-4100
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas.
Xu D, Cao M, Wang B, Bi X, Zhang H, Wu D, Zhang C, Xu J, Xu Z, Zheng D, Chen L, Li P, Wang H, Liu Y, Jiang H, Li K
Theranostics 2023;13(5):1490-1505
Theranostics 2023;13(5):1490-1505
Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling.
Yu C, Zhang X, Wang M, Xu G, Zhao S, Feng Y, Pan C, Yang W, Zhou J, Shang L, Ma Y
Frontiers in oncology 2023;13:1198118
Frontiers in oncology 2023;13:1198118
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma.
Liao C, Li M, Chen X, Tang C, Quan J, Bode AM, Cao Y, Luo X
Journal of experimental & clinical cancer research : CR 2023 Oct 7;42(1):261
Journal of experimental & clinical cancer research : CR 2023 Oct 7;42(1):261
Construction and Evaluation of Novel Dual-function Antifungal Inhibitors and Covalent Organic Framework Carriers Based on the Infection Microenvironment.
Liu Y, Wang Q, Yu S, Liu M, Han J, Sun B
Journal of medicinal chemistry 2023 Oct 12;66(19):13838-13857
Journal of medicinal chemistry 2023 Oct 12;66(19):13838-13857
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy.
Zhang L, Zhao X, Niu Y, Ma X, Yuan W, Ma J
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Journal of extracellular vesicles 2023 Nov;12(11):e12379
Electroacupuncture Alleviates CFA-Induced Inflammatory Pain via PD-L1/PD-1-SHP-1 Pathway.
Deng D, Xu F, Ma L, Zhang T, Wang Y, Huang S, Zhao W, Chen X
Molecular neurobiology 2023 May;60(5):2922-2936
Molecular neurobiology 2023 May;60(5):2922-2936
SHFM1 deficiency suppresses esophageal squamous cell carcinomas progression via modulating NF‑κB signaling and enhancing nature killer cell‑mediated tumor surveillance.
Wu Y, Wang Z, Li S, Chen X, Zhou S
Experimental and therapeutic medicine 2023 May;25(5):195
Experimental and therapeutic medicine 2023 May;25(5):195
Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer.
Wang T, Wu L, Wang S, Shi X, Liu H, Deng W
Chinese journal of natural medicines 2023 May;21(5):333-345
Chinese journal of natural medicines 2023 May;21(5):333-345
PD-L1 Exon 3 Is a Hidden Switch of Its Expression and Function in Oral Cancer Cells.
Yan L, Sun Y, Guo J, Jia R
International journal of molecular sciences 2023 May 3;24(9)
International journal of molecular sciences 2023 May 3;24(9)
Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental analysis.
Qiu J, Wu X, Luo Y, Yao Y, Zhang X, Pan B, Wang X, Tang N
Gene 2023 Mar 10;856:147132
Gene 2023 Mar 10;856:147132
ZNF480 influences the prognosis, pathogenesis, and immune microenvironment in patients with lower-grade glioma.
Zhu Q, Liu Z, Cheng X, Liang W, Wang H, Li P, Zhang J, Chen Y, Gao Y, Qian R
Heliyon 2023 Jul;9(7):e18185
Heliyon 2023 Jul;9(7):e18185
Increased OIT3 in macrophages promotes PD-L1 expression and hepatocellular carcinogenesis via NF-κB signaling.
Wen J, Yang S, Yan G, Lei J, Liu X, Zhang N, Zhang J, Deng H, Wu L, Li Y
Experimental cell research 2023 Jul 15;428(2):113651
Experimental cell research 2023 Jul 15;428(2):113651
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53(flox/+)LSL-Kras(G12D/+)Pdx-1-Cre murine models.
Qiu J, Feng M, Yang G, Cao Z, Liu Y, You L, Zhang T
Cancer letters 2023 Feb 1;554:216020
Cancer letters 2023 Feb 1;554:216020
Inhibition of ACLY overcomes cancer immunotherapy resistance via polyunsaturated fatty acids peroxidation and cGAS-STING activation.
Xiang W, Lv H, Xing F, Sun X, Ma Y, Wu L, Lv G, Zong Q, Wang L, Wu Z, Feng Q, Yang W, Wang H
Science advances 2023 Dec 8;9(49):eadi2465
Science advances 2023 Dec 8;9(49):eadi2465
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
Relationship between the expression of PD-L1 and (18)F-FDG uptake in pancreatic ductal adenocarcinoma.
Li J, Chen R, Chen Y, Xia Q, Zhou X, Xia Q, Wang C, Wan L, Bao H, Huang G, Liu J
British journal of cancer 2023 Aug;129(3):541-550
British journal of cancer 2023 Aug;129(3):541-550
m(6)A reader YTHDF3 is associated with clinical prognosis, related RNA signatures and immunosuppression in gastric cancer.
Yu Y, Meng LL, Chen XY, Fan HN, Chen M, Zhang J, Zhu JS
Cellular signalling 2023 Aug;108:110699
Cellular signalling 2023 Aug;108:110699
Biosynthesized gold nanoparticles that activate Toll-like receptors and elicit localized light-converting hyperthermia for pleiotropic tumor immunoregulation.
Qin H, Chen Y, Wang Z, Li N, Sun Q, Lin Y, Qiu W, Qin Y, Chen L, Chen H, Li Y, Shi J, Nie G, Zhao R
Nature communications 2023 Aug 24;14(1):5178
Nature communications 2023 Aug 24;14(1):5178
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
Peng Z, Lu C, Shi G, Yin L, Liang X, Song G, Tian J, Du Y
European journal of nuclear medicine and molecular imaging 2023 Apr;50(5):1291-1305
European journal of nuclear medicine and molecular imaging 2023 Apr;50(5):1291-1305
The role of YAP1 in survival prediction, immune modulation, and drug response: A pan-cancer perspective.
Hu X, Zhang Y, Yu H, Zhao Y, Sun X, Li Q, Wang Y
Frontiers in immunology 2022;13:1012173
Frontiers in immunology 2022;13:1012173
Bacteria-mediated metformin-loaded peptide hydrogel reprograms the tumor immune microenvironment in glioblastoma.
Zhu L, Liu J, Qiu M, Chen J, Liang Q, Peng G, Zou Z
Biomaterials 2022 Sep;288:121711
Biomaterials 2022 Sep;288:121711
Multimodal Imaging Response after the Singular or Combination Treatments of Vascular Endothelial Growth Factor Inhibitor and Immune Checkpoint Inhibitor.
Ren Y, Pan F, Kan X, Wang J, Han P, Yan J, Li L, Sun P, Liu CY, Bao Q, Yang L, Zheng C
Molecular pharmaceutics 2022 Oct 3;19(10):3664-3672
Molecular pharmaceutics 2022 Oct 3;19(10):3664-3672
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade.
Jiang Y, Yang Y, Hu Y, Yang R, Huang J, Liu Y, Wu Y, Li S, Ma C, Humphries F, Wang B, Wang X, Hu Z, Yang S
Cell reports 2022 Oct 25;41(4):111553
Cell reports 2022 Oct 25;41(4):111553
BMSCs improve TNBS-induced colitis in rats by inducing Treg differentiation by expressing PD-L1.
Gao F, Cui D, Zuo D, Shou Z, Yang J, Yu T, Liu Y, Chu S, Zhu F, Wei C
Biotechnology letters 2022 Nov;44(11):1263-1275
Biotechnology letters 2022 Nov;44(11):1263-1275
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Gong J, Shen Y, Jiang F, Wang Y, Chu L, Sun J, Shen P, Chen M
Oncology letters 2022 May;23(5):148
Oncology letters 2022 May;23(5):148
Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients.
Yu H, Lv W, Tan Y, He X, Wu Y, Wu M, Zhang Q
Journal of translational medicine 2022 Jul 21;20(1):328
Journal of translational medicine 2022 Jul 21;20(1):328
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Liu W, Ren D, Xiong W, Jin X, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Comprehensive analysis of N(6)-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer.
Cui J, Zhu Y, Liu X, Wang W, Jiang X, Xia Y, Zhou G, Chen S, Shi B
Cancer cell international 2022 Feb 11;22(1):72
Cancer cell international 2022 Feb 11;22(1):72
Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment.
Liu Y, Guo Q, Yang H, Zhang XW, Feng N, Wang JK, Liu TT, Zeng KW, Tu PF
ACS central science 2022 Aug 24;8(8):1102-1115
ACS central science 2022 Aug 24;8(8):1102-1115
Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy.
Yao Y, Chen H, Tan N
Acta pharmaceutica Sinica. B 2022 Apr;12(4):2103-2119
Acta pharmaceutica Sinica. B 2022 Apr;12(4):2103-2119
Berry anthocyanidins inhibit intestinal polyps and colon tumors by modulation of Src, EGFR and the colon inflammatory environment.
Mudd AM, Gu T, Munagala R, Jeyabalan J, Fraig M, Egilmez NK, Gupta RC
Oncoscience 2021;8:120-133
Oncoscience 2021;8:120-133
IFNγ/PD-L1 Signaling Improves the Responsiveness of Anti-PD-1 Therapy in Colorectal Cancer: An in vitro Study.
Yuan W, Deng D, Li H, Hu X, Shang X, Hou X, Jiang H, He H
OncoTargets and therapy 2021;14:3051-3062
OncoTargets and therapy 2021;14:3051-3062
c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis.
Zhang L, Wang X, Li Y, Han J, Gao X, Li S, Wang F
Clinical and translational medicine 2021 Sep;11(9):e464
Clinical and translational medicine 2021 Sep;11(9):e464
What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 1: Focus on Immunohistochemical Results with Discussion of Pre-Analytical and Interpretation Variables.
Palicelli A, Bonacini M, Croci S, Magi-Galluzzi C, Cañete-Portillo S, Chaux A, Bisagni A, Zanetti E, De Biase D, Melli B, Sanguedolce F, Ragazzi M, Bonasoni MP, Soriano A, Ascani S, Zizzo M, Castro Ruiz C, De Leo A, Giordano G, Landriscina M, Carrieri G, Cormio L, Berney DM, Athanazio D, Gandhi J, Cavazza A, Santandrea G, Tafuni A, Zanelli M
Cells 2021 Nov 14;10(11)
Cells 2021 Nov 14;10(11)
Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases.
Mu X, Zhang M, Wei A, Yin F, Wang Y, Hu K, Jiang J
Nanoscale 2021 May 21;13(19):8998-9008
Nanoscale 2021 May 21;13(19):8998-9008
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions.
Yu L, Feng R, Zhu L, Hao Q, Chu J, Gu Y, Luo Y, Zhang Z, Chen G, Chen H
Science advances 2020 Nov;6(47)
Science advances 2020 Nov;6(47)
Identification and validation of a combined hypoxia and immune index for triple-negative breast cancer.
Zheng S, Zou Y, Liang JY, Xiao W, Yang A, Meng T, Lu S, Luo Z, Xie X
Molecular oncology 2020 Nov;14(11):2814-2833
Molecular oncology 2020 Nov;14(11):2814-2833
Tumor-associated macrophages induce PD-L1 expression in gastric cancer cells through IL-6 and TNF-ɑ signaling.
Ju X, Zhang H, Zhou Z, Chen M, Wang Q
Experimental cell research 2020 Nov 15;396(2):112315
Experimental cell research 2020 Nov 15;396(2):112315
New insight on the correlation of metabolic status on (18)F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer.
Wang Y, Zhao N, Wu Z, Pan N, Shen X, Liu T, Wei F, You J, Xu W, Ren X
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1127-1136
European journal of nuclear medicine and molecular imaging 2020 May;47(5):1127-1136
Anti-PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells.
Otsuka K, Mitsuhashi A, Goto H, Hanibuchi M, Koyama K, Ogawa H, Ogino H, Saijo A, Kozai H, Yoneda H, Tobiume M, Kishuku M, Ishizawa K, Nishioka Y
Lung cancer (Amsterdam, Netherlands) 2020 Aug;146:86-96
Lung cancer (Amsterdam, Netherlands) 2020 Aug;146:86-96
An update of knowledge on PD-L1 in head and neck cancers: Physiologic, prognostic and therapeutic perspectives.
Lenouvel D, González-Moles MÁ, Talbaoui A, Ramos-García P, González-Ruiz L, Ruiz-Ávila I, Gil-Montoya JA
Oral diseases 2020 Apr;26(3):511-526
Oral diseases 2020 Apr;26(3):511-526
Changes in Tumor-Infiltrating Lymphocytes and Vascular Normalization in Breast Cancer Patients After Neoadjuvant Chemotherapy and Their Correlations With DFS.
Wang Q, Xiang Q, Yu L, Hu T, Chen Y, Wang J, Nie X, Cheng J
Frontiers in oncology 2019;9:1545
Frontiers in oncology 2019;9:1545
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
All-trans retinoic acid induces anti-tumor effects via STAT3 signaling inhibition in oral squamous cell carcinoma and oral dysplasia.
Chen XJ, He MJ, Zhou G
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Oct;48(9):832-839
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Oct;48(9):832-839
Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer.
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, Huang Y, Zhu Y, Shen Y, Zhu Y, Dai B, Hu X, Ye D, Wang Z
Cancer research 2019 May 15;79(10):2604-2618
Cancer research 2019 May 15;79(10):2604-2618
PD-1 Blockade Following Isolated Limb Perfusion with Vaccinia Virus Prevents Local and Distant Relapse of Soft-tissue Sarcoma.
Smith HG, Mansfield D, Roulstone V, Kyula-Currie JN, McLaughlin M, Patel RR, Bergerhoff KF, Paget JT, Dillon MT, Khan A, Melcher A, Thway K, Harrington KJ, Hayes AJ
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Jun 1;25(11):3443-3454
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Jun 1;25(11):3443-3454
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Li J, Yu T, Yan M, Zhang X, Liao L, Zhu M, Lin H, Pan H, Yao M
Experimental cell research 2019 Jan 15;374(2):304-314
Experimental cell research 2019 Jan 15;374(2):304-314
Hyperresponsiveness to interferon gamma exposure as a response mechanism to anti-PD-1 therapy in microsatellite instability colorectal cancer.
Yuan W, Deng D, Jiang H, Tu C, Shang X, He H, Niu R, Dong J
Cancer immunology, immunotherapy : CII 2019 Feb;68(2):257-268
Cancer immunology, immunotherapy : CII 2019 Feb;68(2):257-268
PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling.
Gao H, Zhang J, Ren X
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
The prognostic role of PD-L1 expression for survival in head and neck squamous cell carcinoma: A systematic review and meta-analysis.
Yang WF, Wong MCM, Thomson PJ, Li KY, Su YX
Oral oncology 2018 Nov;86:81-90
Oral oncology 2018 Nov;86:81-90
Programmed death-ligand 1 (PD-L1) expression in pleomorphic carcinoma of the lung.
Imanishi N, Hirai A, Yoneda K, Shimajiri S, Kuwata T, Tashima Y, Takeuchi M, Iwai Y, Ichiki Y, Tanaka F
Journal of surgical oncology 2018 Jun;117(7):1563-1569
Journal of surgical oncology 2018 Jun;117(7):1563-1569
The expression of PD-L1 protein as a prognostic factor in lung squamous cell carcinoma.
Takada K, Okamoto T, Toyokawa G, Kozuma Y, Matsubara T, Haratake N, Akamine T, Takamori S, Katsura M, Shoji F, Oda Y, Maehara Y
Lung cancer (Amsterdam, Netherlands) 2017 Feb;104:7-15
Lung cancer (Amsterdam, Netherlands) 2017 Feb;104:7-15
Associations among pretreatment tumor necrosis and the expression of HIF-1α and PD-L1 in advanced oral squamous cell carcinoma and the prognostic impact thereof.
Chen TC, Wu CT, Wang CP, Hsu WL, Yang TL, Lou PJ, Ko JY, Chang YL
Oral oncology 2015 Nov;51(11):1004-1010
Oral oncology 2015 Nov;51(11):1004-1010
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