EXOC2

gene product
FLJ11026, SEC5L1, Sec5p
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
132 antibodies from 23 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Novus Biologicals
4 antibodies
Atlas Antibodies
1 antibody
antibodies-online
53 antibodies
Invitrogen Antibodies
3 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
2 antibodies
LifeSpan BioSciences, Inc.
14 antibodies
Biorbyt
11 antibodies
GeneTex
4 antibodies
OriGene
3 antibodies
St John's Laboratory
1 antibody
Creative Biolabs
2 antibodies
Acris Antibodies GmbH
1 antibody
MyBioSource
5 antibodies
Creative Diagnostics
3 antibodies
ProSci
1 antibody
Aviva Systems Biology
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
1 antibody