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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB2148A - Provider product page
- Provider
- R&D Systems
- Product name
- Human LDLR APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human LDL R in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDL R, recombinant human LRP-5, or rmLRP-6 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
P01130- Isotype
- IgG
- Antibody clone number
- 472413
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.
Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission.
Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.
Le QT, Blanchet M, Seidah NG, Labonté P
The Journal of biological chemistry 2015 Sep 18;290(38):23385-400
The Journal of biological chemistry 2015 Sep 18;290(38):23385-400
Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission.
Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M Jr, Golden-Mason L, Winn VD, Rosen HR
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 15;195(8):3737-47
Journal of immunology (Baltimore, Md. : 1950) 2015 Oct 15;195(8):3737-47
Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy.
Baldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman ML, Cooper AR, Masiuk K, Hollis RP, Kohn DB
Stem cells (Dayton, Ohio) 2015 May;33(5):1532-42
Stem cells (Dayton, Ohio) 2015 May;33(5):1532-42
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of LDL R in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human LDL R APC-conjugated Monoclonal Antibody (Catalog # FAB2148A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
