LDLR

gene product
LDLCQ2
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
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595 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
116 antibodies
R&D Systems
25 antibodies
GeneTex
12 antibodies
Biorbyt
36 antibodies
NovoPro Bioscience Inc.
19 antibodies
antibodies-online
112 antibodies
Abnova Corporation
8 antibodies
OriGene
8 antibodies
Signalway Antibody LLC
1 antibody
Invitrogen Antibodies
5 antibodies
LifeSpan BioSciences, Inc.
109 antibodies
Proteintech Group
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Abgent
5 antibodies
Acris Antibodies GmbH
11 antibodies
Aviva Systems Biology
3 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
Atlas Antibodies
2 antibodies
NSJ Bioreagents
1 antibody
RabMAbs
2 antibodies
GenWay
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Creative Diagnostics
12 antibodies
Creative Biolabs
7 antibodies
Sino Biological Inc.
12 antibodies
MyBioSource
8 antibodies
BioLegend
1 antibody
St John's Laboratory
2 antibodies
Abbiotec
1 antibody
Abiocode, Inc.
1 antibody
Bethyl Laboratories
1 antibody
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
3 antibodies
United States Biological
42 antibodies
Abbexa
3 antibodies
EMD Millipore
1 antibody