FAB2148P

antibody from R&D Systems

Targeting: LDLR LDLCQ2

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

FAB2148P

Provider

R&D Systems

Product name

Human LDLR PE-conjugated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human LDL R in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDL R, recombinant human LRP-5, or rmLRP-6 is observed.

Reactivity

Human

Host

Mouse

Antigen sequence

P01130


Isotype

IgG

Antibody clone number

472413

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

References

Submitted references

Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes.

Ramanathan A, Gusarova V, Stahl N, Gurnett-Bander A, Kyratsous CA
PloS one 2016;11(4):e0154498

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Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.

Mercer JL, Argus JP, Crabtree DM, Keenan MM, Wilks MQ, Chi JT, Bensinger SJ, Lavau CP, Wechsler DS
PloS one 2015;10(6):e0129776

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Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.

Le QT, Blanchet M, Seidah NG, Labonté P
The Journal of biological chemistry 2015 Sep 18;290(38):23385-400

Flow cytometry

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Detection of LDL R in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human LDL R PE-conjugated Monoclonal Antibody (Catalog # FAB2148P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.