Tissue expression
Cell line expression
Protein structure

HEXB

Hexosaminidase subunit beta
 
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
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281 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
10 antibodies
antibodies-online
76 antibodies
Biorbyt
36 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Affinity Biosciences
1 antibody
OriGene
2 antibodies
GeneTex
2 antibodies
St John's Laboratory
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Acris Antibodies GmbH
1 antibody
Aviva Systems Biology
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Atlas Antibodies
2 antibodies
NSJ Bioreagents
2 antibodies
Boster Biological Technology
2 antibodies
Bioworld Technology, Inc
1 antibody
MyBioSource
5 antibodies
Novus Biologicals
3 antibodies
Abbexa
9 antibodies
Abnova Corporation
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
RabMAbs
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
12 antibodies
Creative Diagnostics
3 antibodies
Leading Biology
3 antibodies
Abgent
1 antibody
EMD Millipore
1 antibody
ProSci
1 antibody
Creative Biolabs
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies