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Learn15591-1-AP
antibody from Proteintech Group
Targeting: SELENOS
AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 15591-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15591-1-AP, RRID:AB_2263813
- Product name
- SELS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SELS antibody (Cat. #15591-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Selenomethionine alleviates chronic heat stress-induced breast muscle injury and poor meat quality in broilers via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Chronic Aroclor 1260 exposure alters the mouse liver proteome, selenoproteins, and metals in steatotic liver disease.
Different Dietary Sources of Selenium Alleviate Hepatic Lipid Metabolism Disorder of Heat-Stressed Broilers by Relieving Endoplasmic Reticulum Stress.
Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Effects of Selenoprotein S Knockdown on Endoplasmic Reticulum Stress in ATDC5 Cells and Gene Expression Profiles in Hypertrophic Chondrocytes.
Maternal Organic Selenium Supplementation Relieves Intestinal Endoplasmic Reticulum Stress in Piglets by Enhancing the Expression of Glutathione Peroxidase 4 and Selenoprotein S.
Transcriptomic analysis reveals the effects of maternal selenium deficiency on placental transport, hormone synthesis, and immune response in mice.
Hydroxy Selenomethionine Alleviates Hepatic Lipid Metabolism Disorder of Pigs Induced by Dietary Oxidative Stress via Relieving the Endoplasmic Reticulum Stress.
Selenoprotein K Is Essential for the Migration and Phagocytosis of Immature Dendritic Cells.
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
Dietary selenium sources differentially regulate selenium concentration, mRNA and protein expression of representative selenoproteins in various tissues of yellow catfish Pelteobagrus fulvidraco.
Quantitative proteomics reveals potential anti-inflammatory protein targets of radial extracorporeal shock wave therapy in TNF-α-induced model of acute inflammation in primary human tenocytes.
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Comprehensive Analysis of Expression and Prognostic Value of Selenoprotein Genes in Thyroid Cancer.
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Hydroxy Selenomethionine Improves Meat Quality through Optimal Skeletal Metabolism and Functions of Selenoproteins of Pigs under Chronic Heat Stress.
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Selenogenome and AMPK signal insight into the protective effect of dietary selenium on chronic heat stress-induced hepatic metabolic disorder in growing pigs.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells.
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Jing J, Wang J, Xiang X, Yin S, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:363-375
Chronic Aroclor 1260 exposure alters the mouse liver proteome, selenoproteins, and metals in steatotic liver disease.
Piell KM, Petri BJ, Xu J, Cai L, Rai SN, Li M, Wilkey DW, Merchant ML, Cave MC, Klinge CM
Environmental toxicology and pharmacology 2024 Apr;107:104430
Environmental toxicology and pharmacology 2024 Apr;107:104430
Different Dietary Sources of Selenium Alleviate Hepatic Lipid Metabolism Disorder of Heat-Stressed Broilers by Relieving Endoplasmic Reticulum Stress.
Wang J, Jing J, Gong Z, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Kang B, Che L, Zhao H
International journal of molecular sciences 2023 Oct 22;24(20)
International journal of molecular sciences 2023 Oct 22;24(20)
Selenoproteins synergistically protect porcine skeletal muscle from oxidative damage via relieving mitochondrial dysfunction and endoplasmic reticulum stress.
Jing J, He Y, Liu Y, Tang J, Wang L, Jia G, Liu G, Chen X, Tian G, Cai J, Che L, Kang B, Zhao H
Journal of animal science and biotechnology 2023 Jun 4;14(1):79
Journal of animal science and biotechnology 2023 Jun 4;14(1):79
Effects of Selenoprotein S Knockdown on Endoplasmic Reticulum Stress in ATDC5 Cells and Gene Expression Profiles in Hypertrophic Chondrocytes.
Wang H, Li Z, Liu Y, Zhang M, Shi Y, Zhang Y, Mi G, Wang M, He Y, Chen Y, Chen C, Chen J
Biological trace element research 2023 Apr;201(4):1965-1976
Biological trace element research 2023 Apr;201(4):1965-1976
Maternal Organic Selenium Supplementation Relieves Intestinal Endoplasmic Reticulum Stress in Piglets by Enhancing the Expression of Glutathione Peroxidase 4 and Selenoprotein S.
Ding D, Mou D, Zhu H, Jiang X, Che L, Fang Z, Xu S, Lin Y, Zhuo Y, Li J, Huang C, Zou Y, Li L, Wu D, Feng B
Frontiers in nutrition 2022;9:900421
Frontiers in nutrition 2022;9:900421
Transcriptomic analysis reveals the effects of maternal selenium deficiency on placental transport, hormone synthesis, and immune response in mice.
Cheng W, Zhang L, Sa P, Luo J, Li M
Metallomics : integrated biometal science 2022 Sep 12;14(9)
Metallomics : integrated biometal science 2022 Sep 12;14(9)
Hydroxy Selenomethionine Alleviates Hepatic Lipid Metabolism Disorder of Pigs Induced by Dietary Oxidative Stress via Relieving the Endoplasmic Reticulum Stress.
Jing J, Yin S, Liu Y, Liu Y, Wang L, Tang J, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Antioxidants (Basel, Switzerland) 2022 Mar 15;11(3)
Antioxidants (Basel, Switzerland) 2022 Mar 15;11(3)
Selenoprotein K Is Essential for the Migration and Phagocytosis of Immature Dendritic Cells.
Xia H, Wang Y, Dai J, Zhang X, Zhou J, Zeng Z, Jia Y
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
He Y, Liu Y, Tang J, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Dietary selenium sources differentially regulate selenium concentration, mRNA and protein expression of representative selenoproteins in various tissues of yellow catfish Pelteobagrus fulvidraco.
Xu XJ, Zhang DG, Zhao T, Xu YH, Luo Z
The British journal of nutrition 2022 Feb 28;127(4):490-502
The British journal of nutrition 2022 Feb 28;127(4):490-502
Quantitative proteomics reveals potential anti-inflammatory protein targets of radial extracorporeal shock wave therapy in TNF-α-induced model of acute inflammation in primary human tenocytes.
Ge R, Zhu Q, Liu D, Zhang Q, Jiang S, Yu X, Shu J, Gao F, Guo J, Chen S, Gao B
Heliyon 2022 Dec;8(12):e12008
Heliyon 2022 Dec;8(12):e12008
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Xiong Y, Li B, Li J, Jin E, He S
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Comprehensive Analysis of Expression and Prognostic Value of Selenoprotein Genes in Thyroid Cancer.
Zhao Y, Chen P, Lv HJ, Wu Y, Liu S, Deng X, Shi B, Fu J
Genetic testing and molecular biomarkers 2022 Apr;26(4):159-173
Genetic testing and molecular biomarkers 2022 Apr;26(4):159-173
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Zhang ZH, Cao XC, Peng JY, Huang SL, Chen C, Jia SZ, Ni JZ, Song GL
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Hydroxy Selenomethionine Improves Meat Quality through Optimal Skeletal Metabolism and Functions of Selenoproteins of Pigs under Chronic Heat Stress.
Liu Y, Yin S, Tang J, Liu Y, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Antioxidants (Basel, Switzerland) 2021 Sep 29;10(10)
Dietary Marginal and Excess Selenium Increased Triglycerides Deposition, Induced Endoplasmic Reticulum Stress and Differentially Influenced Selenoproteins Expression in the Anterior and Middle Intestines of Yellow Catfish Pelteobagrus fulvidraco.
Zhang DG, Zhao T, Xu XJ, Lv WH, Luo Z
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Antioxidants (Basel, Switzerland) 2021 Mar 29;10(4)
Selenogenome and AMPK signal insight into the protective effect of dietary selenium on chronic heat stress-induced hepatic metabolic disorder in growing pigs.
Liu Y, Tang J, He Y, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Journal of animal science and biotechnology 2021 Jun 12;12(1):68
Journal of animal science and biotechnology 2021 Jun 12;12(1):68
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
Deficiency of VCP-Interacting Membrane Selenoprotein (VIMP) Leads to G1 Cell Cycle Arrest and Cell Death in MIN6 Insulinoma Cells.
Men L, Sun J, Ren D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(5):2185-2197
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(5):2185-2197
Selenoprotein S protects against adipocyte death through mediation of the IRE1α-sXBP1 pathway.
Men L, Yu S, Yao J, Li Y, Ren D, Du J
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Biochemical and biophysical research communications 2018 Sep 18;503(4):2866-2871
Selenium-sensitive miRNA-181a-5p targeting SBP2 regulates selenoproteins expression in cartilage.
Min Z, Guo Y, Sun M, Hussain S, Zhao Y, Guo D, Huang H, Heng L, Zhang F, Ning Q, Han Y, Xu P, Zhong N, Sun J, Lu S
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
Journal of cellular and molecular medicine 2018 Dec;22(12):5888-5898
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15591-1-AP(SELS antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SELS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SELS. This antibody recognizes human,mouse,rat antigen. The SELS antibody has been validated for the following applications: ELISA, WB, IP analysis.
