SELENOS

gene product
AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP
This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019). [provided by RefSeq, Jul 2017]
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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Novus Biologicals
7 antibodies
antibodies-online
56 antibodies
Abnova Corporation
6 antibodies
Invitrogen Antibodies
2 antibodies
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
14 antibodies
Cell Signaling Technology, Inc
2 antibodies
Bethyl Laboratories
1 antibody
Biorbyt
9 antibodies
OriGene
3 antibodies
Aviva Systems Biology
1 antibody
Abbiotec
1 antibody
Boster Biological Technology
1 antibody
ProSci
1 antibody
St John's Laboratory
1 antibody
MyBioSource
3 antibodies
Creative Biolabs
2 antibodies
United States Biological
4 antibodies
Creative Diagnostics
3 antibodies
GeneTex
1 antibody