Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- NBP1-06640 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-06640, RRID:AB_1582401
- Product name
- Rabbit Polyclonal Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.
Endogenous hydrogen sulfide regulates histone demethylase JMJD3-mediated inflammatory response in LPS-stimulated macrophages and in a mouse model of LPS-induced septic shock.
Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury.
Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.
The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition.
Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness.
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan NL, Wang R, Wang YJ, Semenza GL
The Journal of clinical investigation 2020 Jul 27;
The Journal of clinical investigation 2020 Jul 27;
Endogenous hydrogen sulfide regulates histone demethylase JMJD3-mediated inflammatory response in LPS-stimulated macrophages and in a mouse model of LPS-induced septic shock.
Liu S, Wang X, Pan L, Wu W, Yang D, Qin M, Jia W, Xiao C, Long F, Ge J, Liu X, Zhu Y
Biochemical pharmacology 2018 Mar;149:153-162
Biochemical pharmacology 2018 Mar;149:153-162
Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury.
Luo X, Yang D, Wu W, Long F, Xiao C, Qin M, Law BY, Suguro R, Xu X, Qu L, Liu X, Zhu YZ
Cardiovascular research 2018 Dec 1;114(14):1894-1906
Cardiovascular research 2018 Dec 1;114(14):1894-1906
Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.
Luo T, Dunphy PS, McBride JW
Frontiers in cellular and infection microbiology 2017;7:178
Frontiers in cellular and infection microbiology 2017;7:178
The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition.
Taube JH, Sphyris N, Johnson KS, Reisenauer KN, Nesbit TA, Joseph R, Vijay GV, Sarkar TR, Bhangre NA, Song JJ, Chang JT, Lee MG, Soundararajan R, Mani SA
Oncotarget 2017 Sep 12;8(39):65548-65565
Oncotarget 2017 Sep 12;8(39):65548-65565
Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.
Pham D, Yu Q, Walline CC, Muthukrishnan R, Blum JS, Kaplan MH
Journal of immunology (Baltimore, Md. : 1950) 2013 Jul 15;191(2):902-11
Journal of immunology (Baltimore, Md. : 1950) 2013 Jul 15;191(2):902-11
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [NBP1-06640] - Total protein from human HepG2 and mouse 3T3 cells was separated on a 7.5% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/mL anti-JMJD3 in 1% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [NBP1-06640] - Analysis of JMJD3 expression on HepG2 whole cell lysates.