KDM6B

gene product
JMJD3, KIAA0346
The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
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344 antibodies from 28 providers.

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antibodies-online
98 antibodies
Novus Biologicals
27 antibodies
Biorbyt
18 antibodies
GeneTex
2 antibodies
LifeSpan BioSciences, Inc.
76 antibodies
OriGene
8 antibodies
NSJ Bioreagents
6 antibodies
Abgent
4 antibodies
Arigo
1 antibody
Invitrogen Antibodies
4 antibodies
Abnova Corporation
5 antibodies
Acris Antibodies GmbH
7 antibodies
Aviva Systems Biology
4 antibodies
SignalChem
1 antibody
ProSci
4 antibodies
NovoPro Bioscience Inc.
1 antibody
MyBioSource
9 antibodies
Creative Biolabs
5 antibodies
Creative Diagnostics
3 antibodies
R&D Systems
1 antibody
United States Biological
50 antibodies
EMD Millipore
2 antibodies
Active Motif
1 antibody
Affinity Biosciences
1 antibody
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Sigma-Aldrich
3 antibodies