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Protein structure
FBXL18
F-box and leucine rich repeat protein 18Fbl18, FLJ11467
The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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| antibodies-online |  ABIN393741 |
5 references | Monoclonal |
WB
EL
IHC
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| Novus Biologicals | H00080028-M01 |
Monoclonal |
WB
EL
IHC
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| Abnova Corporation | H00080028-M01 |
Monoclonal |
WB
EL
IHC
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| LSBio | LS-C105178 |
Monoclonal |
WB
EL
|
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| Invitrogen Antibodies | PA5-109255 |
Polyclonal |
WB
IHC
FC
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