RCHY1

The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]

Description

ring finger and CHY zinc finger domain containing 1

Protein family

Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

4:q21.1 (75479037 - 75514764)

Ensembl ID

ENSG00000163743  (ver. 99.38)

Orthologs

Mouse Rchy1: ENSMUSG00000029397

UniProt

Q96PM5

neXtProt

NX_Q96PM5

Human splice variants
Mouse splice variants