FNab05373

antibody from FineTest Biotech

Targeting: MSH3 DUP, MRP1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab05373 - Provider product page
Provider: FineTest Biotech
Product name: MSH3 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops(IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: mutS homolog 3
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MSH3 protein structure - FNab05373 shown in red.