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Protein structure
MSH3
MutS homolog 3DUP, MRP1
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-29829 |
1 references | Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 22393-1-AP |
2 references | Polyclonal |
WB
EL
IP
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| Novus Biologicals | NBP2-19417 |
1 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN968513 |
4 references | Monoclonal |
WB
ICC
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| Affinity Biosciences | DF7457 |
Polyclonal |
WB
EL
ICC
IHC
|
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