Tissue expression
Cell line expression
Protein structure
EEF1E1
Eukaryotic translation elongation factor 1 epsilon 1AIMP3, P18
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
3 references | Polyclonal |
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antibodies-online | ![]() |
Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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