Tissue expression
Cell line expression
Protein structure
BMP3
Bone morphogenetic protein 3This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Proteintech Group | 1 references | Polyclonal |
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| antibodies-online | 3 references | Polyclonal |
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| Abnova Corporation | 3 references | Polyclonal |
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| Affinity Biosciences | Polyclonal |
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